The senator said it was 'impossible' Russia had no involvement.
"Now, whether it’s actually a Russian military person who pushed the button or not, they had to train these people for a period of time to make them capable of launching this system," Sen. McCain said.
"The point here is that Vladimir Putin is literally getting away with murder ... and we are doing little in response. I think the investigation has to continue, we have to do everything we can to take care of the loved ones in the terrible tragedy that's taken place, but for us not to point the finger of blame exactly where it belongs - there's ample, overwhelming evidence. And not only because of this particular act, but because of Vladimir Putin's continued aggression and fomenting of aggression in Ukraine."
WATCH INTERVIEW ABOVE
RELATED: Who are Ukraine's pro-Russia rebels?
CNN's Chris Cuomo is on the ground reporting from eastern Ukraine and covering all the angles of the Malaysia Airlines Flight 17 crash.
Cuomo interviewed Alex Borodai, the leader of the self-declared Donetsk People's Republic, on "New Day" Monday.
He asked Borodai about accusations that his forces shot down the plane but the local rebel leader rejected these claims and pointed the blame back at the Ukraine.
Former President Bill Clinton acknowledges he got "very close" to helping achieve peace in the Middle East shortly before ending his eight years in office.
Over a two-week period in 2000, Clinton played host at Camp David to then-Israeli Prime Minister Ehud Barak and Palestinian Authority Chairman Yasser Arafat.
The summit ultimately ended without agreement. Two U.S. presidents later, the conflict rages on.
Now, Clinton is less optimistic Middle East negotiators will get that close again, telling CNN that peace between Israel and the Palestinians is impossible until Hamas renounces violence.
"There is no way the Israelis are going to give up the West Bank and agree to a state unless Hamas agrees to give up violence and recognizes Israel's right to exist," he said in the interview airing Monday on "New Day."
Chris is live in eastern Ukraine this morning with updates at 6am ET on CNN.
You can see images he's captured on the ground HERE.