January 16th, 2014
09:25 AM ET

FDA: Acetaminophen Doses Over 325 mg Might Lead to Liver Damage

You're in pain after surgery, and your doctor prescribes you Vicodin, or maybe Percocet. But when you get home, the pain hasn't subsided and you decide to pop some Extra Strength Tylenol.

Unknowingly, you may have just taken more of the drug acetaminophen than is safe.

Acetaminophen is often used in pain medications with opioids such as oxycodone (Percocet), hydrocodone (Vicodin) and codeine (Tylenol with Codeine). These are called combination drugs, and the Food and Drug Administration is asking doctors to stop prescribing those that have more than 325 mg of acetaminophen per dose.

The FDA says no data show that taking more than that amount provides enough benefit to outweigh the risk of liver damage.

"Many consumers are often unaware that many products (both prescription and OTC) contain acetaminophen, making it easy to accidentally take too much," the FDA said in a statement Tuesday.

The warning does not apply to over-the-counter drugs such as Tylenol, which contains acetaminophen. The FDA said it will address over-the-counter products in another regulatory action.

In 2011, the FDA asked manufacturers to limit the amount of acetaminophen in prescription combination drugs to 325 mg per capsule or tablet by January 2014. While more than half of the manufacturers agreed, some combination drugs with higher amounts of acetaminophen remain on the market.

The federal agency says it plans to start the process of withdrawing approval of prescription combination drugs from manufacturers that have not complied.

See more at CNN.comĀ 

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soundoff (4 Responses)
  1. intrasurgicals

    I read your blog.. its amazing. you having very good content. very helpful to all. Thanks for sharing this
    Surgical product Manufacturer and Suppliers
    Infusion Set and Syringes Manufacturer and suppliers

    February 4, 2014 at 4:31 am | Reply
  2. unitechplctrainingseo

    I read your blog.. its amazing. you having very good content. very helpful to all.
    Surgical product Manufacturer and Suppliers
    Infusion Set and Syringes Manufacturer and suppliers

    February 1, 2014 at 7:58 am | Reply
  3. intrasurgicalseo

    I read your blog.. its amazing. you having very good content. very helpful to all.
    Surgical product Manufacturer and Suppliers
    Infusion Set and Syringes Manufacturer and suppliers

    January 21, 2014 at 7:14 am | Reply
  4. Bayousara

    This has nothing to do with aspirin! So why your headline?

    January 16, 2014 at 9:19 pm | Reply

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